#3 Christiane Nüsslein-Volhard

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When the Nobel Prize in Phy­sio­lo­gy or Me­di­ci­ne was awarded to Chris­tia­ne Nüss­lein-Volhard in 1995, it caused a minor sen­sa­ti­on. Only a handful of women had been re­co­gni­zed by the Nobel Com­mit­tee at that timea si­tua­ti­on that has been slow to change since. Nüss­lein-Volhard, a German de­ve­lop­men­tal bio­lo­gist who had been working as di­rec­tor of the Max Planck In­sti­tu­te for De­ve­lop­men­tal Biology in Tü­bin­gen since 1985, was the­re­fo­re not only a pioneer in her field but also, as a woman working in fun­da­men­tal re­se­arch, a role model for the next ge­nera­ti­on of female sci­en­tists. Decades later, she would re­mem­ber vividly just how hard she had to fight for equa­li­ty and re­co­gni­ti­on while com­ple­ting her PhD in Tü­bin­gen because people be­lie­ved she was less capable than her male col­leagues.

She re­cei­ved the Nobel Prize for her sys­te­ma­tic genetic ana­ly­sis of the fruit fly (Dro­so­phi­li­dae), through which she was able to de­mons­tra­te that there are par­al­lels in em­bryo­nic de­ve­lop­ment between insects and ver­te­bra­tes. After decades of sta­gna­ti­on in this area, she was the first re­se­ar­cher to show the mor­pho­ge­ne­tic pro­ces­ses in genes and their in­flu­ence on the for­ma­ti­on and co­lo­ring of phy­si­cal or­ga­nisms. Her life­time re­se­arch goal was to iden­ti­fy the genes re­spon­si­ble for phe­no­ty­pic va­ria­ti­on in the evo­lu­tio­na­ry process.

That is pre­cise­ly what she talks about in this re­cor­ded lecture given on July 30, 2018, at the Okinawa In­sti­tu­te of Science and Tech­no­lo­gy in Japan. She dis­cus­ses the fun­da­men­tal ques­ti­ons of modern de­ve­lop­men­tal biology: the role of genes in forming pat­terns, com­ple­xi­ty, and di­ver­si­ty. In her lecture, which starts at the five-minute mark and lasts just under an hour, Nüss­lein-Volhard looks back over her own re­se­arch career, which re­flec­ts the almost uni­ver­sal themes of modern ge­ne­tics. It seems ge­ne­tics is a di­sci­pli­ne that poses similar ques­ti­ons to those asked in many of the social sci­en­ces and hu­ma­nities: ques­ti­ons con­cer­ning how the part relates to the whole, the func­tions of norms and de­via­ti­ons, and the causes of di­ver­si­ty, beauty, and va­ria­ti­on. In her trade­mark sci­en­ti­fic and ob­jec­tive style, Nüss­lein-Volhard reveals cu­rio­si­ty as the key driving force behind every sci­en­ti­fic finding—and so­me­thing that we might call a trans­di­sci­pli­na­ry search for the origins of our world.

Peter-André Alt

Date July 30, 2018
Length 77 mins
Title, series Animal Beauty: Func­tion and Evo­lu­ti­on of Bio­lo­gi­cal Ae­s­the­tics, OIST Pre­si­den­ti­al Lecture Series #2
Lan­guage English
Video Okinawa In­sti­tu­te of Science and Tech­no­lo­gy (OIST)